Steve and Snot's friendship is put to the test when their mothers get in a fight.
Stan insists everyone help him recreate the rustic family ski trips of his childhood while Klaus falls in love with a tech support operator.
To save a beloved restaurant from closing, Stan must bring the 1950s back to Langley.
Francine is jealous of the new and improved Klaus and vows to take him down.
Stan and Francine inject some much-needed fire into their relationship.
Wheels and the Legman try to hunt down the perpetrators who destroyed Steve's secret swimming hole. Meanwhile, Klaus helps an aging Principal Lewis reclaim his confidence.
The Smiths return from a difficult, quarrelsome vacation, but they can't get a break from each other.
Francine's newfound friendship with a frog brings excitement to the whole Smith household. Unfortunately, it drives their neighbor, Greg, crazy.
Steve goes on a class trip to Philadelphia, where he hopes to fall in love.
Roger is forced to confront himself after a series of accidents. Klaus and Jeff bond.
Steve profiles Stan for an essay contest at school; Francine uses a porta john.
Roger and Steve try to save a dying mall.
Worried that he's not smart enough for Hayley, Jeff undergoes an experimental intelligence enhancement procedure at the CIA. Roger recruits Steve to help him harvest snake venom.
Stan becomes infatuated with a doll that the CIA wants to use to spy on the Russians.
Stan moves to Chicago to become a comic while Steve and Hayley host Roger for a nice night in.
Steve and Jeff try to bond as brothers while the rest of the family visits an escape room.
When the family goes to a dude ranch, Klaus and Rogu have to work together to survive in the wilderness.
Steve spins out about his future, but a radio show about new age mysticism gives him a hopeful new understanding of life. Roger struggles to get into the adult film industry.
After a series of boring personas, Roger goes to great lengths to prove to Francine he still has "his edge".
Stan tries a new, cutting edge parenting approach DNA splicing.
American Dad becomes the 25th scripted prime-time show in the History of Television to reach 300 episodes and Roger's past comes back to haunt him.
After Stan's plan for the perfect Christmas goes terribly, tragically wrong, he's given a magical opportunity to make things right.