Overwhelmed with financial troubles, Mort asks Peter and Quagmire to help him save his pharmacy. However, things take a turn for the worse when the trio decides to burn it down to collect insurance money.
When Peter and Chris go away to fat camp, they cross paths with a serial killer who targets overweight kids. Meanwhile, Stewie is traumatized by the frightening cover of a Queen album.
After a car accident, Peter, Brian, Joe, and Quagmire wake up in a hospital with no memory and discover that they're the last people left on Earth.
After Peter's favorite children's television show gets cancelled, he takes matters into his own hands by creating and starring in his own show for kids. Meanwhile, Meg begins an internship at the hospital with Dr. Hartman.
Stewie meets a little girl who might be his soulmate; Lois buys twin beds after Peter repeatedly crushes her in his sleep.
