The adventures of the Griffins, an eccentric family living in New England, who are led by father Peter and mother Lois.
At the vet's office, Brian meets a female show dog named Ellie. Smitten with her, he enters a show dog competition, in which the winner gets to breed with her.
In Part One of a special two-part story, Brian meets and quickly falls in love with a woman named Jess, who reveals she has cancer. After she receives devastating news regarding her diagnosis, Brian proposes marriage to her.
In Part Two of a special two-part story, Brian's marriage to Jess is not what he envisioned, especially after her miraculous recovery from cancer.
Brian worries about the legacy he's leaving behind, so Stewie makes a robot duplicate as a living biography.