Peter and his friends take full advantage of Quagmire's "family and friends" airline discount and decide to take a trip to San Francisco. While flying back to Quahog, the plane they're on gets hi-jacked by three terrorists.
Peter and the gang realize their new neighbor is none other than the New England Patriot's tight end, Rob Gronkowski.
Peter, Joe, Cleveland, and Quagmire want to do an activity together so they decide to start a podcast. After a horrendous start, Peter accidently plays multiple songs and is mistaken for a DJ by a club owner.
Peter and Lois receive a note from Principal Shepherd pinned to Chris' backpack. During their meeting they learn that if Chris doesn't pass his upcoming history exam he will have to repeat the 9th grade.
Meg is worried that she won't do well on her SATs, so she convinces Brian to take the test for her. A confident Brian agrees to the challenge, and even dresses up like Meg, only to find out that he received the lowest score in the class.
At Stewie's graduation, Brian states that Stewie's proud moment is no big feat. Stewie takes it upon himself to try and acquire some real world knowledge. Meg is discovered by a photographer who asks her if she would like to model for him.
When Meg asks Peter for a check for her upcoming field trip, he finally notices that his "checkbook" is just a blank pad of paper. Lois agrees to take Peter to the bank where they discover that Peter's first name is really "Justin".
When Stewie complains that his tricycle has been stolen, Peter and his friends are spurred into action. Peter finds the kid responsible, and the success leads the group to start a detective agency for kids.
Stewie fears that he and Brian are growing apart after Brian avoids several invitations to hangout. In an effort to rekindle their friendship, Stewie decides that having a baby would bring them back together.
After Cleveland diffuses an argument between Quagmire and Joe, Peter encourages him to open his own therapy office. Meanwhile, Meg gets a job as a TSA agent, and revels in the positive attention she gets for being the "office hottie".
After Brian gets diagnosed with liver disease from his heavy drinking, Peter is stuck with the task of inserting Brian's suppository pills. When Brian bites Peter's arm in self-defense, Brian becomes the alpha dog.
While watching a celebrity roast with Brian, Peter is inspired to throw a roast for himself, but it backfires when his friends go further then he expected. Hurt by what was said, Peter decides to seek out a new group of friends.
Joe decides to become more spontaneous and independent, leaving Bonnie and quitting his job. This "New Joe" invites the guys on a road trip to Niagara Falls to celebrate.