Space Ghost loses the show to the owner of a liquor store, and he is forced to use a shark as the show's new mascot. A bear wanders onto the set, upsetting the normal routine by repeatedly attacking Space Ghost. Later, the shark explodes, attracting giant Space Bees.
Space Ghost has a temper tantrum and he leaves the show. While he's gone, Zorak, Moltar and Dave Thomas have a great time. Meanwhile, Space Ghost tries to make friends with the superheroes at the Hole of Justice, but they beat him up.
Moltar gets his chance to host the show while Space Ghost illegally copies the new Radiohead album. Later, it is revealed that Space Ghost is married to Bjork. Space Ghost ends the episode by knocking her off of a cliff.
Space Ghost is hosting a "mystery dinner theater" and the guest star is Busta Rhymes. After causing a massive gas leak, Space Ghost beats Zorak senseless a number of times. Later, they end up at a grocery store, confusing it for a hospital.
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