Using the time machine, Stewie and Brian accidentally travel outside the space-time continuum, where Stewie causes an explosion that creates the universe; Bertram travels back in time to kill one of Stewie's ancestors: Leonardo da Vinci.
After Brian is thrown in jail for drug possession, he decides to launch a campaign to have marijuana legalized; when Mayor West finally passes the law, the entire town of Quahog literally goes to pot.
Peter hosts three adaptations of Stephen King tales: "Stand By Me," "Misery" and "The Shawshank Redemption."
The Griffins discover that the evil monkey in Chris's closet isn't so evil after all; Stewie befriends Miley Cyrus, who turns out to be an android.
Peter's ham radio communicates with the ghost of Ronald Regan; Quagmire discovers he fathered a baby girl; Stewie has himself cloned.
A fight over a chew-rope with Peter leaves Brian toothless and disfigured. But after a visit with QuagmireÆs dentist, Brian puts his new ôtoothyö smile to the test, as a real estate agent.
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