The Monarch launches his first attack on his new arch nemesis, the other Dr. Venture. But Jonas has the formidable defenses of Spider-Skull Island on his side, as well as his own Team Venture, and the expert advice of a trio of O.S.I. "butterfly specialists." It will take a loose reading of the Guild handbook, an insertion team of his three best henchmen, and all the diabolical chicanery The Monarch can muster to even the playing field.
A series of cryptic clues sends Team Venture out to uncover a mystery left by the late Jonas Venture, Sr. As each new solved riddle exposes one more piece of secret Venture history, Brock discovers that his long-standing role as Dr. Venture's bodyguard may not have been the assignment he always thought it was.
Brock Samson is a marked man. Terminated from the O.S.I., stripped of his license to kill, and hunted by three of the world's deadliest assassins, Brock only has one thing left: The Venture family. And he wants them as far away from him as they can get. But not even Molotov Cocktease, Hunter Gathers and a friendly pair of ex-O.S.I. comrades can sever the ties that bind. And The Monarch and Sgt. Hatred certainly aren't helping.
Heads will fly as the explosive conclusion of The Venture Bros. two-part season finale finds Brock and the Venture family on the run from the Law, The Monarch, Sgt. Hatred and the entire O.S.I.! Only bald ingenuity and an unlikely ally can possibly save their necks from the deadly noose tightening around the Venture Compound, but they stand to lose so much more when they learn the hard way that you can't go home again.
Questions are answered and truths are revealed. Learn how Henchman 21 copes with life without 24. See what happens when Brock and the Venture family are forced to part ways. Discover the final fate of H.E.L.P.eR. And all the while, the balance of the free world hangs in the hands of Dean Venture, who must kill Hitler.