Ryuko has been deeply hurt by the discovery of who and what she really is, and the words of those around her fall on deaf ears. Turning her blade on Mikisugi and the others Ryuko slices down a building and then leaves Osaka.
Satsuki Kiryuin has been using Life Fibers, the source of the Goku Uniforms' power, in her plot to conquer all of the nation's academies. To fight back, Ryuko's father, Isshin Matoi created a Kamui, a uniform woven entirely of Life Fibers.
Ryuko wakes up to find everyone in a tizzy. Today is "Honnouji Academy No-Late Day," held each semester by the Disciplinary Committee. They set countless traps on the route to school, and if a student is late they are summarily expelled.
Ryuko is defeating Honnouji Academy's club presidents at a steady pace when Tsumugu Kinagase appears before her. Kinagase wields a machine gun that neutralizes the abilities of Goku Uniforms. He can hold off even Two-Star club presidents.
One of the Elite Four, Uzu Sanageyama, speaks directly with Satsuki and is given permission to face Ryuko in battle. Sanageyama's astonishing dynamic visual acuity allows him to anticipate his opponent's every move and get the drop on them.
The anti-Life Fiber resistance group Nudist Beach had an underground lair beneath Dotonbori. Mikisugi and Tsumugu return as the group's combatants gear up for battle.
Ryuko is thrown for a loop when her fight against Kiryuin is saddled with such grand themes as "humanity" and "alien life." Mikisugi informs Ryuko that Senketsu was created specifically for her for the purpose of opposing the Life Fibers.
Everyone is celebrating the conquest that was made possible by the Tri-City Schools Raid Trip. Satsuki announces that the Cultural & Sports Grand Festival will be held to honor the arrival of Ragyo Kiryuin, the academy's director.
Satsuki reveals that everything she has done was in ruse meant to conceal her betrayal from Ragyo, and that Honnouji Academy is a fighting force she built up in preparation for a war against both Ragyo and the Life Fibers.
Ryuko is shocked to find herself still alive, even though her heart has been ripped out of her chest. Ryuko's body has been impregnated with Life Fibers.
Ryuko in Junketsu and Satsuki in Senketsu. The battle of these sisters of twisted fate has begun. Senketsu tries to talk Ryuko, who is drunk on the pleasure of wearing Junketsu, into taking off the other Kamui.
After tearing at her Life Fibers in a burst of rage and ripping off Junketsu, Ryuko merges with Senketsu once again. Ryuko tells Nui that the crucial difference between them is that Ryuko is surrounded by "people who make no sense".
Mako has stepped forward to join the battle. Ryuko and Satsuki leave her behind on the ship and set out for the Original Life Fiber, which is carrying Ragyo.
Shinra-Koketsu's power is the ability to force all Life Fibers, including Kamui and Goku Uniforms, into absolute submission. In the final stages of the battle, Ryuko and the others completely lose their ability to fight.
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