The Smith family forgets to celebrate Father's Day, and so to make it up to Stan, they plan out the perfect day. Stan uses a CIA device to erase their memories and have them continually plan perfect days for him.
Stan goes over-the-top to produce a reenactment of Charles Lindbergh's solo flight for Steve's school project after he gets an F. Klaus buys a pair of shoes online and Hayley helps him harass the neighbor they believe has stolen them.
Stan is embarrassed when a painting of Francine's genitals, done by a famous artist, is unveiled at the museum. Steve turns to helping people after masturbation is ruined by his mom's portrait.
Stan is upset at the idea of becoming a grandfather after Hayley and Jeff announce they're trying to have a baby. Steve and Klaus join a drug gang after Steve decides to take being an uncle extra seriously.
Stan sets out to stop a tree that he considers his father from being cut down. Steve realizes he's stopped growing and considers surgery.
Steve joins the high school water polo team in order to get girls. Meanwhile, Roger and Stan get a boat.
Hayley mentally regresses to a six-year-old. Steve and his pals get a slow cooker.
Steve goes to work with Stan and discovers the N.S.A. Hayley decides to let go of being a vegetarian and eat meat for one day.
Stan, tattooed and haunted, travels a barren Langley Falls alone. Meanwhile, a mysterious element known as The Two Hundred has reigned terror on the town and separated Stan from his family.
Jeff returns from space...Or does he? Meanwhile, Steve watches after Snot's hamster.
American Dad is sold to a Chinese businessman. Meanwhile, Stan has Francine committed to an insane asylum when he forgets their anniversary.
When Stan lies about his texting and driving accident, he takes a seizure medication and suffers from the side effects. Meanwhile, Roger helps Steve with his performance anxiety.
Roger, Francine, Hayley, and Klaus head off to the Chimdale Spa for a week of relaxation, but instead are hounded by nosey hotel detective, Ron Turlington. Back at home, Steve discovers that Stan is bald.
Fed up with a lack of alone time, Stan starts taking experimental CIA pills that allow him to remain awake 24/7.
Roger is on the outs with Stan and the family when they discover he has been seeing other families behind their back. Before they can truly forgive him, Roger must overcome his family infidelity.
Stan turns to smuggling when trans fat is banned from Langley Falls. But when Inspector Turlington of the Langley Falls police becomes suspicious of Stan, Stan recruits Steve into his illegal enterprise. Now Steve must find a way to keep the trans fat flowing while under Turlington's watch. Meanwhile, Roger helps Klaus claim an inheritance.
After term limits force Stan out of his position as president of the HOA, Roger steps in as the new leader under the guise of one Roy Rogers McFreely. Roger uses his power to pass new resolutions and by-laws solely to anger Stan, who earlier refused to buy Roger grenadine. Stan teams up with Hayley and plots to have Roger removed from office.
When Stan's con-man dad Jack resurfaces in prison awaiting trial for a crime he did not commit, Steve gets Stan to let Jack stay with them under house arrest.
When snobby rich kid Etan steals Steve's girlfriend Debbie, Steve concocts a scheme to get revenge. Aided by Roger, Toshi, and Barry, Steve plots to rob Etan's Bar Mitzvah and get back his girlfriend. But when the plan goes awry and Snot takes the blame, Steve must decide whether to tell the truth and clear Snot's name or remain silent and get back Debbie. Meanwhile, Stan and Francine pitch an idea to a cell phone company.
Stan reveals to Francine that, in the case she should die, he has a back up wife. Enraged with Stan, Francine takes Jim, one of Stan's CIA buddies, as her back up husband.
The Smiths find out that their outstanding family vacations have only been experiences in virtual reality. Stan vows to redeem himself by taking the family on a cruise, but when they are stranded on a remote island, things get out of hand.
Stan tries to get an unsuspecting Jeff Fischer out of his life for good by taking him on a road trip to Florida, where there is a warrant out for Jeff's arrest.